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Transjugular Intrahepatic Portosystemic Shunt, commonly referred to as TIPS, is a minimally invasive interventional procedure primarily designed to alleviate portal hypertension, a condition often resulting from chronic liver disease. Portal hypertension occurs when there is an increased pressure in the portal venous system, which can lead to life-threatening complications such as variceal bleeding, ascites, and hepatic encephalopathy. The TIPS procedure involves creating a channel between the portal circulation and the systemic venous circulation to bypass the liver and reduce the pressure in the portal system. This is achieved by inserting a stent-graft through the jugular vein in the neck, navigating down to the liver, and creating a pathway within the liver between the portal vein and one of the hepatic veins. The stent maintains the patency of this channel, allowing excess blood flow to bypass the liver, which significantly reduces portal pressure. The procedure is usually performed under fluoroscopic guidance, often in conjunction with ultrasound, providing real-time imaging to ensure accurate placement of the stent. TIPS can be a lifeline for patients who do not respond to medical management or those for whom invasive surgical procedures are too risky. The benefits of TIPS include rapid alleviation of portal hypertension symptoms, improved quality of life, and decreased hospitalization rates for related complications. However, the procedure is not without risks; potential complications can include stent occlusion, liver failure, infection, and encephalopathy due to the diversion of blood away from hepatic metabolism. Long-term outcomes can vary, with some patients experiencing significant symptom relief while others may require further intervention or medical management. Patient selection is crucial, as TIPS is typically reserved for specific cases where conservative treatments have failed and where the potential benefits outweigh the risks. Post-procedure management includes careful monitoring of liver function and potential complications, with some patients requiring repeat sessions to maintain shunt patency. In addition, individuals will typically be managed with medications to address underlying liver disease and prevent complications. In conclusion, TIPS represents a significant advancement in the management of portal hypertension, providing a minimally invasive option for patients facing life-altering symptoms and complications from liver disease, ultimately facilitating improved patient outcomes and quality of life. However, careful consideration must be given to patient eligibility and ongoing management post-procedure to ensure the benefits of this intervention are fully realized.